What is nephrotic syndrome?

Nephrotic syndrome is a group of symptoms that indicate your kidneysare not working properly. These symptoms include

Your kidneys are made up of about a million filtering units called nephrons. Each nephron includes a filter, called the glomerulus, and a tubule. The glomerulus filters your blood, and the tubule returns needed substances to your blood and removes wastes và extra water, which become urine. Nephrotic syndrome usually happens when the glomeruli are inflamed, allowing too much proteinlớn leak from your blood inlớn your urine.

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As blood passes through healthy kidneys, the glomeruli filter out waste products và allow the blood to keep the cells và proteins the toàn thân needs.

How common is nephrotic syndrome?

Nephrotic syndrome is a combination of symptoms that can occur due khổng lồ different causes. Aý muốn adults, the syndrome is most often caused by rare kidney diseases.

Who is more likely khổng lồ develop nephrotic syndrome?

Nephrotic syndrome can affect children và adults of all ages.1

What are the complications of having nephrotic syndrome?

Nephrotic syndrome can lead khổng lồ serious complications, including2

higher risk of infection caused by the loss of immunoglobulins, proteins in your blood that help fight viruses & bacteria

What are the symptoms of nephrotic syndrome?

Symptoms of nephrotic syndrome can include3

puffy eyelids & swelling in the legs, ankles, feet, lower abdomen, or other parts of your toàn thân foamy urine weight gain due lớn retaining too much fluid tiredness loss of appetite

What causes nephrotic syndrome?

Many disorders can cause nephrotic syndrome, including diseases that affect only the kidneys & diseases that affect many parts of the body toàn thân, such as diabetes& lupus.

Kidney diseases

Diseases that affect only the kidneys & lead lớn nephrotic syndrome are called primary causes of nephrotic syndrome. The most common primary causes of nephrotic syndrome are3

Other causes

Other causes of nephrotic syndrome, also called secondary causes, include3

diabetes lupus some allergic reactions

How vị health care professionals diagnose nephrotic syndrome?

Your health care professional can diagnose nephrotic syndrome through urine tests. The urine tests show if you are losing too much protein in your urine.

Tests for diagnosing nephrotic syndrome

Urine dipstichồng thử nghiệm. This simple test checks for albumin in your urine. Having albumin in the urine is called albuminuria. You collect the urine sample in a container during a visit to lớn a health care professional’s office or lab. A health care professional places a strip of chemically treated paper, called a dipstiông xã, into lớn the urine for the kiểm tra. The dipstiông chồng changes color if albumin is present in the urine.

To confirm the diagnosis of nephrotic syndrome, your health care professional may order one of these two urine tests

24-hour urine collection. For this thử nghiệm, you will need to lớn collect urine samples over 24 hours. Your health care professional will then sover the samples to lớn a lab for analysis.

Your health care professional may also order blood tests khổng lồ check for low levels of protein in your blood and other problems linked to nephrotic syndrome.

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Tests for identifying the cause

Once nephrotic syndrome has been diagnosed, your health care professional will use tests to lớn identify what caused it và check your kidney function. Tests for finding the cause of nephrotic syndrome can include3

blood tests

How vày health care professionals treat nephrotic syndrome?

Treating symptoms và complications

Treatment varies according to symptoms, causes, & the extent of kidney damage. Symptoms of nephrotic syndrome are most often treated with these medicines3

In some cases, your health care professional may also prescribe medicines that lower cholesterol, called statins. Blood thinners may also be used, but usually only if you develop a blood clot.

People with nephrotic syndrome should receive the pneumococcal vaccine, along with yearly flu shots, to lớn prsự kiện viral and bacterial infections.

Treating underlying causes

Other treatments vary, depending on underlying causes. In some cases, you may need to take medicines that suppress your immune system. For more on how health care professionals treat the underlying causes of nephrotic syndrome, see the stamboom-boden.com health topic Glomerular Diseases.

Once the cause has been treated, nephrotic syndrome may go away & kidney function returns to lớn normal. Some patients may experience periods of remissionfollowed by times when symptoms reappear. In some cases, nephrotic syndrome may lead lớn kidney failure.

How does eating, diet, and nutrition affect nephrotic syndrome?

Eating, diet, và nutrition have sầu not been shown lớn play a role in causing or preventing nephrotic syndrome. However, if you have sầu developed nephrotic syndrome, your health care professional may recommend that you

limit intake of sodium (salt) và fluids khổng lồ help control swelling reduce the amount of fat and cholesterol in your diet to help control your blood cholesterol levels

Clinical Trials for Nephrotic Syndrome

The stamboom-boden.com conducts & supports clinical trials in many diseases & conditions, including kidney diseases. The trials look lớn find new ways khổng lồ prsự kiện, detect, or treat disease and improve sầu chất lượng of life.

What are clinical trials for nephrotic syndrome?

Clinical trials—and other types of clinical studies—are part of medical research and involve sầu people lượt thích you. When you volunteer to take part in a clinical study, you help doctors và researchers learn more about disease & improve sầu health care for people in the future.

Researchers are studying many aspects of nephrotic syndrome, such as

the kidney diseases that can lead khổng lồ nephrotic syndrome, including genes that may cause these diseases quality of life amuốn people with nephrotic syndrome how to best treat nephrotic syndrome

Find out if clinical studies are right for you.

Watch a video clip of stamboom-boden.com Director Dr. Griffin P.. Rodgers explaining the importance of participating in clinical trials.

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